Jan Marc Orenstein, MD, PhD

Professor of Pathology, GWU SMHS

Current HIV/AIDS Educational Activities:

• Lecture to second year medical students on Pathology of HIV/AIDS
• Lecture to pathology residents on Pathology of HIV/AIDS
• Lecture to pathology residents on gastrointestinal disease in HIV/AIDS
• Lecture to pathology residents on Ultrastructural pathology of surgical specimens from patients with HIV/AIDS

Current HIV/AIDS Clinical Activities:

• Diagnostic pathology of gastrointestinal specimens (biopsies and resections) from patients with HIV/AIDS
• Perform diagnostic electron microscopy on surgical specimens from patients with HIV/AIDS

Current HIV/AIDS Research Activities:

• Development of human adaptive immune system in cord blood-transplanted mice.
• Effect of HAART on ultrastructure of mitochondria in peripheral blood cells, fat, and skeletal muscle from patients with HIV/AIDS
• Localization of enzyme markers in Pneumocystis jirovecii organisms
• HIV infection and replication by macrophages. Effect of HAART on morphology of mitochondria