The Institute for Genomic Research (TIGR) is a nonprofit research institute with interests in structural, functional, and comparative analysis of genomics and gene products in viruses, eubacteria, pathogenic bacteria, archea, and eukaryotes, including humans.

TIGR is an international resource and possibly the premier center in the world for genomics research. The Institute first attained international acclaim when in 1995 TIGR scientists reported the completed sequence of the genome for the human pathogen Haemophilus influenzae. This was the first time that the entire genome of a free-living organism had been demonstrated. Later in that year, the genome of Mycoplasma genitalium was completely sequenced. Since then, TIGR has completed the sequence of a number of microbial genomes and will soon have the complete sequence of the 14 microbial genomes (including agents that cause syphilis, meningitis, cholera, tuberculosis, and lyme disease), 5 parasite genomes (including the etiologic agents of malaria, African sleeping sickness, and chagas disease), human chromosome 16, and several plant genomes. The data from TIGR's research effort is used by researchers from around the world in the quest to conquer disease and hunger.

TIGR is located in Rockville, MD, in the greater Washington, DC metropolitan area, and consists of more than 80,000-square feet of laboratory and office space located on a 12-acre campus. The Institute has a large DNA sequencing laboratory and has modern facilities for bioinformatics, biochemistry, and molecular biology.