Research Interests

Chemical and biological properties of the thymosins; Study of the endocrine role of the thymus gland in relation to aging processes; Mechanism of action of thymic hormones, cytokines, and biological response modifiers; ß-thymosins in actin-sequestration, treatment of diseases associated with actin toxicities, inflammation, and septic shock; Thymosin ß4 in wound healing and angiogenesis; Role of thymosin ß4 in cardiac repair and neuroplasticity; and Thymosin ß4 and stem cell maturation

Selected Publications

• Goldstein, A.L. and Goldstein, A.L. From Lab to Bedside: Emerging Clinical Applications of Thymosin a1. Expert Opinion. 9:1-16, 2009.
• Goldstein, A.L. and Garaci, E. (eds). Thymosins in Health and Disease. New York Academy of Sciences, 1112, 2007.
• Goldstein, A.L. The History of the Development of the Thymosins. New York Academy of Sciences. 1112: 1-13, 2007.
• Baix, X., Wu, J., Zhang, Q., Alesci, S., Manoli, I., Blackman, M., Goldstein, A.L., Rennert, O.M., Su, Y.A. 2007. The Third-Generation Human Mitochondria-focused cDNA Microarray (nMitChip3) and its Bioinformatics for Analysis of Gene Expression. Biotechniques. 42:365-375, 2007.
• Rubin, B.K., Kater, A.P., Goldstein, A.L. Thymosin ß4 Sequesters Actin in Cystic Fibrosis Sputum and Decreases Sputum Cohesivity in Vitro. Chest. 130:1433-1440, 2006.
• Goldstein, A.L., Hannappel, E., and Kleinman, H.K. Thymosin ß4: Actin-Sequestering Protein Moonlights to Repair Injured Tissues. Trends in Molecular Medicine. 11:421-429, 2005.